Clinical Trials & Studies

Below are opportunities to participate in a clinical trial or study. There are therapeutic trials where either experimental or known drugs are used, and there are also observational studies where no drugs are used.

Please contact us if you have questions or need help in determining which study is right for you.


Enroll-HD is a worldwide observational study. It will monitor how the disease appears and changes over time in different people, and is open to people who either have HD or are at-risk as well as their family members and caregivers.

Learn more about Enroll-HD

LEGATOHDlogoA multinational, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of laquininmod as treatment in patients with Huntington’s Disease.

Learn more about LEGATO-HD

SIGNAL A Phase II research trial for people who are at risk for Huntington Disease (HD) and have early signs of HD. The study will assess the safety, tolerability, and effectiveness of VX15 (a novel monoclonal antibody).

Learn more about SIGNAL

A randomized, double blind Phase II research study of the effects of pridopidine in patients with Huntington disease.

Learn more about Pride-HD



The study will assess if the investigational drug PF-02545920 is safe and if it will have beneficial effects in participants with Huntington’s disease.

Learn more about Amaryllis