Clinical Trials & Studies

Below are opportunities to participate in a clinical trial or study. There are therapeutic trials where either experimental or known drugs are used, and there are also observational studies where no drugs are used.

Please contact us if you have questions or need help in determining which study is right for you.


Enroll-HD is a worldwide observational study. It will monitor how the disease appears and changes over time in different people, and is open to people who either have HD or are at-risk as well as their family members and caregivers.

Learn more about Enroll-HD

LEGATOHDlogoA multinational, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of laquininmod as treatment in patients with Huntington’s Disease.

Learn more about LEGATO-HD

The purpose of the study is to find out the prevalence of the SNP1 and/or SNP2 in HD patients. The study consists of one visit for a brief exam and blood specimen collection.  The results will be used as a potential pre-screening tool for the PRECISION-HD study.  It is expected that about 20-30% of patients will not have SNP1 or SNP2 and will therefore be ineligible for the PRECISION-HD study.

 Learn more about WAVE SNP1 & SNP2

SIGNAL A Phase II research trial for people who are at risk for Huntington Disease (HD) and have early signs of HD. The study will assess the safety, tolerability, and effectiveness of VX15 (a novel monoclonal antibody).

Learn more about SIGNAL

A randomized, double blind Phase II research study of the effects of pridopidine in patients with Huntington disease.

Learn more about Pride-HD